Company Category: Research

Simpson Biotech Co., Ltd.

Simpson Biotech Co., Ltd. (SBC), a private Co. founded in 1998, located in Taiwan is focusing on: (I). Medicinal fungus fermentation & enzymatically hydrolyzed bioactive natural ingredients used for dietary supplements, cosmetics & drug discovery. (II). OEM/ODM services for Recombinant Proteins (i.e. Industrial Enzymes), using a patented starch-binding protein as the affinity tag. New product launched in 2023: 1. Antrodia cinnamomea extract as natural ingredient for cosmetics formulation, 2. Potent anti-yeast & anti-bacteria soluble chitosan for food/drug & agriculture applications; 2. World’s first high purity (chitobiose+chitotriose > 90%) oligo chitosan for weight, diabetes and triglyceride control; 3. Hydrolyzed Fucoidan for immune & glucose control. SBC has won numerous awards with 54 patents issued. —–>—– 【Natural Compound as Oral Drug development for NAFLD/NASH】  Reduce liver triglyceride and cholesterol in NAFLD  Reduce serum triglyceride and cholesterol in NAFLD  Reduce liver fat deposition in NAFLD  Reduce ALT and AST in NAFLD  Anti-inflammation and oxidative stress  Anti-fibrosis  US, CN, TW patents granted 【Recombinant Protein Expression/Purification Platform (HERPEPSTM) and Products】  Patent Recombinant Protein Platform & CDMO Service – Cost-effective recombinant protein expression & purification system; From gene to protein  Starch Binding Protein (SBP) as an affinity tag  One-step purification of recombinant protein by starch  Protein immobilization on starch enhanced the thermostability & shelf life  Easy to scale up: From 100L lab-scale concept proof to 8000L mass production  Ideal for industrial, food, feed enzymes  Self-owned Tool Box for Protein Expression in Pichia pastoris  Methanol-induced or Methanol-free expression  Antibiotics-free expression host  Genetic manipulation of expression strain with high yield  Cost can be 12%) of Simpson Biotech’s currently marketed dietary supplement actually illustrates both the safety and the effectiveness of the mycelia and the compound of Hepasim® through human clinical studies. One clinical study for Rheumatoid Arthritis (RA) has been completed. Initial results from the clinical study plus the previous metabolic/pharmacokinetic animal studies on these compounds already illustrate that Hepasim® is a promising NCE drug candidate. 【Fermented natural products for dietary supplement】  Alcoholic Hangover Release : Antrodia cinnamomea mycelia  Neuroprotective & Memory Enhancement : Ginsenoside compound K  Immune Regulation : Cordyceps sinensis mycelia, Hydrolyzed Fucoidan  Male Hormone (Testosterone) Stimulant : Cordyceps sinensis mycelia  Heart Protection : Agaricus blazei murill  Increase Stamina : low molecular weight functional peptides from casein, whey, soy, collagen, silk  OEM/ODM Fermentation : Cordyceps sinensis, Phellinus linteus, Ganoderma lucidum, Agaricus blazei murill and other mycelia and their extracts  Fermented Vegetables & Grains Concentrate as prebiotics  Cosmetics for skin whitening & anti-scar : Antrodia cinnamomea extract 【Immune booster for IFN-γ stimulation as anti-viral and antibiotic alternative feed additive】 LZ-8 is a fungal immunomodulatory protein originally isolated from the popular oriental medicinal fungus. Oral administration of rLZ-8 stimulates IFN-γ secretion. It is not only a good dietary supplement for humans but also an antibiotic alternative for animal additives for the prevention of virus or coccidia infection in field studies. Possible pharmaceutical applications per oral include immune-regulatory diseases.  IFN-γ Stimulant  Anti-viral  Antibiotic alternative  Anti-coccidia  Increase feed efficiency  US, TW, CN patent granted (US9950028, I589586, CN106232133A) | Simpson Biotech Co., Ltd. (SBC), a private Co. founded in 1998, located in Taiwan is focusing on: (I). Medicinal fungus fermentation & enzymatically hydrolyzed bioactive natural ingredients used for dietary supplements, cosmetics & drug discovery. (II). OEM/ODM services for Recombinant Proteins (i.e. Industrial Enzymes), using a patented starch-binding protein as the affinity tag and in-house non-methanol, antibiotics-free expression strain. Highlight in 2024: 1. Recombinant protein OEM/ODM with proprietary yeast platform, 2. Antrodia cinnamomea extract as natural ingredient for cosmetics formulation. 3. Antrodin as potent oral drug for NAFLD/NASH; 4. Natural anti-yeast & anti-bacteria soluble chitosan for food/drug & agriculture applications; SBC has won numerous awards with 54 patents issued. —–>—– 【Recombinant Protein OEM/ODM with Proprietary Yeast Platform】 – One-step purification of recombinant protein by starch – Protein immobilization on starch enhanced the thermostability & shelf life – Easy to scale up: From 100L lab-scale concept proof to 8000L mass production – Ideal for industrial, food, feed enzymes – Turn-key licensed(non-exclusive) to global feed company already > – In-house Non-Methanol promoter compared to AOX1 – Antibiotics-free expression strain: Eco-friendly – Genetic manipulation of expression strain with high yield – Cost can be 12%) of Simpson Biotech’s currently marketed dietary supplement actually illustrates both the safety and the effectiveness of the mycelia and the compound of Hepasim® through human clinical study for Rheumatoid Arthritis (RA). – Initial results from the clinical study plus the previous metabolic/pharmacokinetic animal studies on these compounds already illustrate that Hepasim® is a promising NCE drug candidate. 【Fermented natural products for dietary supplement】 – Alcoholic Hangover Release : Antrodia cinnamomea mycelia – Neuroprotective & Memory Enhancement : Ginsenoside compound K – Immune Regulation : Cordyceps sinensis mycelia, Hydrolyzed Fucoidan – Male Hormone (Testosterone) Stimulant : Cordyceps sinensis mycelia – Heart Protection : Agaricus blazei murill – Increase Stamina : low molecular weight functional peptides from casein, whey, soy, collagen, silk – OEM/ODM Fermentation : Cordyceps sinensis, Phellinus linteus, Ganoderma lucidum, Agaricus blazei murill and other mycelia and their extracts – Fermented Vegetables & Grains Concentrate as prebiotics – Cosmetics for skin whitening & anti-scar : Antrodia cinnamomea extract 【Immune booster for IFN-γ stimulation as anti-viral and antibiotic alternative feed additive】 LZ-8 is a fungal immunomodulatory protein originally isolated from the popular oriental medicinal fungus. Oral administration of rLZ-8 stimulates IFN-γ secretion. It is not only a good dietary supplement for humans but also an antibiotic alternative for animal additives for the prevention of virus or coccidia infection in field studies. Possible pharmaceutical applications per oral include immune-regulatory diseases. – IFN-γ Stimulant – Anti-viral – Antibiotic alternative – Anti-coccidia – Increase feed efficiency – US, TW, CN patent granted (US9950028, I589586, CN106232133A) | Simpson Biotech Co., Ltd. specializes in bio-fermentation development and commercialization: 1. Medicinal fungi for dietary supplements and early-stage drug discovery, specifically Hepasim®. 2. SimpsonPure health supplements portfolios. 3. Patented platform developing for recombinant protein expression and purification. We are seeking partnerships for the development of new recombinant proteins.

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Simbex

Simbex enables innovators to bring transformative technologies to market through premier engineering and strategic consulting. For more than 25 years, we have applied deep expertise across product design and development, quality and regulatory, reimbursement, and market intelligence to support hundreds of med tech, sports tech, and health tech programs.We engage as a trusted partner, flexible in structure and rigorous in execution. Clients bring us in to accelerate critical decisions, de-risk complex development paths, and augment internal teams with the exact capabilities needed at each stage. Our engagement models range from targeted advisory and rapid technical sprints to embedded, cross-functional program teams that scale with your needs without sacrificing quality or accountability.Our clients include grant-backed startups seeking experienced guidance, rapidly scaling venture-funded organizations, and strategic enterprises looking to extend their internal capacity and move faster with confidence. | Simbex enables innovators to successfully bring medical devices, consumer health products and sports technologies to market through premier engineering and strategic consulting.Find the Simbex booth for a chance to be selected for a Phase 0 MasterPlan™ valued up to $50,000, and more!

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SILLO

SILLO Link Glove is a wearable hand sensor that accurately digitizes human hand movements and tactile sensations. It features a total of 41 integrated sensors, including 16 proprietary fiber-based strain sensors on the back of the hand for measuring joint flexion and 25 pressure sensors on the palm to detect localized force.

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Silcotech North America Inc.

Silcotech, a global leader in LSR injection molding for medical, healthcare, automotive, packaging and consumer electronics markets.Our manufacturing facility with our specialized staff serve a global customer base for their design, tool-making and manufacturing needs. From simple projects to those with complex requirements, our vision boils down to commitment to be the most technically advanced silicone molder in the industry. Our core competency is providing automated, mass production, liquid injection molding solutions from concept to serial production.For decades, Silcotech has worked at local, national and global levels to provide solutions that meet the highest standards of quality, performance, and value.Our services include: DFM, Prototyping, Tool Design, Tool Engineering, Mass Production, Multi-Shot Silicone and Silicone-Thermoplastic Molding. | Silcotech North America is a global leader in liquid injection molding for the medical, automotive, household consumer, consumer electronics and solar industry. Silcotech’ s core competence is providing turn-key solutions for simple to most complex part geometries in moderate to high volumes in clean-room environments. Capabilities and value added services: • 2-Component Silicone Molding • Silicone Micro-molding • In house tool design, engineering, prototyping Silcotech is an ISO 9001:2015, ISO 13485:2016 and ISO 14001:2015 registered company utilizing lean Six Sigma, GMP and Risk Assessment. Silcotech is FDA 21 CFR 820 compliant. Silcotech has locations in Canada, the United States and India. | Silcotech North America Inc. is a global leader in technologically-advanced liquid injection molding solutions for the medical, healthcare, automotive, packaging, consumer electronics and other markets. Expertise includes fully automated manufacturing, turnkey solutions, multi material molding, micromolding, prototyping, six sigma, GMP, FDA compliance and risk assessment. Other capabilities consist of complex part geometries in moderate to high volumes in cleanroom environments. ISO certified. In-house tool design and complete automation, product design, engineering and prototyping.

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Sikich

Sikich LLP is a business and technology consultancy who’s close to 1,500 team members provide advisory, consulting, and technology services to clients in life sciences, manufacturing, professional services, and other industries. The company’s life sciences practice spans the industry and supports more than 200 life sciences clients, including biotechnology and biopharmaceutical companies, CROs, and lab diagnostic companies. As a leading life science technology consultant, we can help you streamline operations and ensure compliance, allowing stakeholders to do what they do best: develop new medicines for patients who need them. | At Sikich, we empower life sciences organizations through strategic planning, regulatory expertise, and digital modernization. From inception to commercialization, we specialize in planning, regulatory, quality, and compliance, leveraging cutting-edge technologies like Oracle NetSuite, Honeywell’s TrackWise Digital, and Kneat’s solutions to streamline operations and accelerate innovation. Our tailored approach combines deep industry knowledge with advanced digital tools, ensuring compliance, enhancing efficiency, and reducing time-to-market for life-changing therapies. A focus on built in audit trails, roles-based control and automated reporting ensure compliance with FDA 21 CFR Part 11, SOX and EU Annex 11. With a commitment to precision, integrity, and transformation, we help companies navigate complex regulatory landscapes and embrace the future of life sciences with confidence. Plan smarter. Modernize faster. Innovate with impact.

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Sika Automotive AG

Sika is a specialty chemicals company with a leading position in the development and production of systems and products for sealing, bonding, damping, reinforcing, and protecting in the building sector and industrial manufacturing. With subsidiaries in 103 countries and over 400 factories worldwide, Sika drives innovation and sustainability in construction and industrial manufacturing. The company employs 33,700 people and generated CHF 11.2 billion in net sales in 2025.

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SigutLabs s.r.o.

SigutLabs, a contract research organization (CRO) located in Prague, Czech Republic, helps businesses from small start-ups to pharmaceutical giants overcome their chemistry challenges. Our agile PhD chemists specialize in custom synthesis, scale-up, and contract research across organic, bioorganic, and medicinal chemistry, with a focus on nucleotide and nucleoside chemistry, ADC linkers, and advanced applications. We excel at developing novel synthetic routes for undescribed compounds and custom synthesis of known molecules, also offering dedicated FTE chemists. We have a lean team of up to 10 employees with every chemist holding a PhD degree, which is an industry-leading scientific staff ratio. All our experts studied at prestigious universities and have extensive experience in organic and medicinal chemistry from top international institutions. Our cutting-edge labs prioritize a sustainable future with eco-friendly practices and invest in top-tier equipment to handle your most complex projects. Products from our inventory are available for purchase through our e-shop, ensuring super-fast and secure delivery worldwide. Founded in 2011, SigutLabs has grown from a small lab to a partner of choice for leading pharmaceutical and Silicon Valley companies. We played a major role in the fight against COVID-19 by developing a new synthetic pathway of remdesivir for research in just four months, and were recognized for our achievements with the 2023 Company of the Year award (Central Bohemia region). Fueled by a vision to build on the legacy of Czech chemistry, exemplified by Prof. Antonín Holý and his groundbreaking molecule tenofovir, we aim to re-establish the Czech Republic’s position on the global chemistry map. We can tackle your toughest challenges with our team’s diverse chemistry experience, including: ADC linkers Heterocyclic chemistry Palladium-catalyzed reactions Organometallic chemistry Nucleoside/nucleotide chemistry Fluorine chemistry Photochemistry Supramolecular chemistry Total synthesis of natural products Modification of enzyme substrates/inhibitors Visit our website at www.sigutlabs.com to see how SigutLabs frees hands, saves costs, and accelerates your projects with our outsourced chemistry expertise. Follow us on LinkedIn to see the latest news. | x

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Sigmund Lindner GmbH

Sigmund Lindner GmbH is a German family owned company with more than 170 years of experience and know-how for the production of technical glass beads as well as more than 20 years of experience in development and production of high-quality ceramic grinding media. The products are used in many applications, among others also for the preparation and processing of battery materials. Sustainability and innovation are top priorities for us. This is reflected in our certification to ISO 50001 and ISO 14001 and the goal of being CO2 neutral according to Scope 1 and Scope 2 by 2025 and the availability of our sustainability report.

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Siemens Healthineers

Siemens Healthineers pioneers breakthroughs in healthcare. For everyone. Everywhere. Sustainably. The company is a global provider of healthcare equipment, solutions and services, with activities in more than 180 countries and direct representation in more than 70 and has approx. 72,000 employees. As a leading medical technology company, Siemens Healthineers is committed to improving access to healthcare for underserved communities worldwide and is striving to overcome the most threatening diseases. The company is principally active in the areas of imaging, diagnostics, cancer care and minimally invasive therapies, augmented by digital technology and artificial intelligence. | Learn more about stroke solutions from Siemens Healthineers www.siemens-healthineers.us/stroke-care | We pioneer breakthroughs in healthcare. For everyone. Everywhere. Sustainably. The innovative healthcare solutions offered by Siemens Healthineers are crucial for making high-quality healthcare accessible for everyone, for clinical decision-making, and for treatment pathways. We are a team of more than 73,000 Healthineers in over 70 countries passionately pushing the boundaries of what is possible in healthcare to help improve the lives of people around the world.

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Sichuan SEVC Testing Technology Co., Ltd.

Sichuan SEVC Testing Technology Co., Ltd., incubated by Prof. Ouyang Minggao Academician Workstation (Sichuan New Energy Vehicle Innovation Center), is a public technical service platform affiliated to the Key Laboratory of Energy Storage and Power Battery Safety under the State Administration for Market Regulation. Specializing in battery safety, we provide testing, certification, failure analysis, accident investigation, safety assessment, modeling and simulation. Supported by Tsinghua University, we offer full-lifecycle intelligent services for battery materials, cells and systems. We are expanding into low-altitude vehicles, embodied intelligence, zero-carbon energy and new energy storage. Headquartered in Yibin with bases across China, we have 40,000 m² of laboratory space, over 5,000 instruments and 80+ patents. Accredited with CMA and CNAS, we promote global green transformation and foster new-quality productive forces.

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