TruDiagnostic
Lexington, United States of America
Overview
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About
About TruDiagnostic TruDiagnostic Most biomarkers tell you where a patient is right now. DNA methylation tells you where they're headed and why. TruDiagnostic is a CLIA-certified epigenetics lab and research partner specializing in DNA methylation analysis for biological age, disease risk, and multi-system health performance. Founded in 2020, we've built one of the largest private methylation datasets in the world: 200,000+ participants, 80+ published studies, and 115+ active research collaborators - including institutions publishing in Nature Aging and peer-reviewed clinical journals. Our positioning is deliberate: science over commercialization. Every product we offer is grounded in rigorous, independently validated research. What we bring to the table for our partners: Our Epigenetic Biomarker Proxies (EBPs) predict 2,000+ protein and metabolite biomarkers directly from a blood spot. In head-to-head comparisons, these DNA Methylation derived biomarkers outperform traditional direct measurements 62% of the time, with better effect sizes and greater signal stability. Unlike point-in-time assays, methylation patterns reflect long-term biological averages, making them less susceptible to day-to-day biological noise. Our Methylation Risk Scores (MRS) predict 5- and 10-year disease risk with ~90% accuracy across cardiovascular disease, diabetes, Alzheimer's, Parkinson's, and cognitive decline. Unlike polygenic risk scores, MRS are modifiable — they respond to interventions, making them uniquely actionable for clinical trials, therapeutic validation, and personalized medicine applications. Our immune deconvolution platform reconstructs cell-type composition from whole blood with only a 3% error rate compared to flow cytometry, at a fraction of the cost and complexity. We collaborate across pharma, consumer health, and clinical research. Deliverables include processed IDAT files and beta values, custom aging clocks, organ-specific risk scores, cohort-level analysis reports, and intervention efficacy assessments. Our work with Olaplex on tissue-specific skin aging demonstrates how this technology extends well beyond blood. If you're running clinical trials, building risk stratification tools, or looking for a methylation data partner with the depth to support real discovery, we're built for that conversation.
- Website
- https://trudiagnostic.com
- Phone
- 859 797 2983
- Address
- 881 Corporate Dr., Lexington KY 40503, United States of America
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