Company Category: Research Technology

SigutLabs s.r.o.

SigutLabs, a contract research organization (CRO) located in Prague, Czech Republic, helps businesses from small start-ups to pharmaceutical giants overcome their chemistry challenges. Our agile PhD chemists specialize in custom synthesis, scale-up, and contract research across organic, bioorganic, and medicinal chemistry, with a focus on nucleotide and nucleoside chemistry, ADC linkers, and advanced applications. We excel at developing novel synthetic routes for undescribed compounds and custom synthesis of known molecules, also offering dedicated FTE chemists. We have a lean team of up to 10 employees with every chemist holding a PhD degree, which is an industry-leading scientific staff ratio. All our experts studied at prestigious universities and have extensive experience in organic and medicinal chemistry from top international institutions. Our cutting-edge labs prioritize a sustainable future with eco-friendly practices and invest in top-tier equipment to handle your most complex projects. Products from our inventory are available for purchase through our e-shop, ensuring super-fast and secure delivery worldwide. Founded in 2011, SigutLabs has grown from a small lab to a partner of choice for leading pharmaceutical and Silicon Valley companies. We played a major role in the fight against COVID-19 by developing a new synthetic pathway of remdesivir for research in just four months, and were recognized for our achievements with the 2023 Company of the Year award (Central Bohemia region). Fueled by a vision to build on the legacy of Czech chemistry, exemplified by Prof. Antonín Holý and his groundbreaking molecule tenofovir, we aim to re-establish the Czech Republic’s position on the global chemistry map. We can tackle your toughest challenges with our team’s diverse chemistry experience, including: ADC linkers Heterocyclic chemistry Palladium-catalyzed reactions Organometallic chemistry Nucleoside/nucleotide chemistry Fluorine chemistry Photochemistry Supramolecular chemistry Total synthesis of natural products Modification of enzyme substrates/inhibitors Visit our website at www.sigutlabs.com to see how SigutLabs frees hands, saves costs, and accelerates your projects with our outsourced chemistry expertise. Follow us on LinkedIn to see the latest news. | x

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Shanghai OPM Biosciences Co., Ltd

OPM Biosciences (Stock Code: 688293) is a leading provider of Cell Culture Media (CCM) and CDMO (Contract Development and Manufacturing Organization) services. We offer an integrated solution to meet the needs of biopharmaceutical companies worldwide. OPM was established in 2013 dedicated to total cell culture solution development, which has resulted in our fast growth. We are proud to be the first listed CCM company in China and committed to being a total solution provider in biologics development. Our management system is certified to ISO9001:2015 by TÜV NORD. We have four fully cGMP-compliant plants, covering an overall area of 18,000m². Currently, we are constructing a new 30,000m² headquarters to meet the growing demand for our products and services. OPM is becoming a strategic partner of biopharmaceutical companies worldwide, and our dedication to quality and innovation ensures that we continue to be a trusted partner in the industry. Our CCM solutions are renowned for their innovative chemically-defined/serum-free media design and manufacturing. We offer a range of products and services, including proprietary commercial media, customized formulations, and OEM solutions for our clients’ unique cell lines. Our exceptional performance has established us as the preferred supplier for over 230 biologics (IND or BLA) worldwide. In addition, OPM’s CDMO services provide efficient End-to-End solutions for biotherapeutic protein development and manufacturing. Our cGMP-compliant facilities support all stages of biologics development, from antibody discovery to IND and BLA manufacturing up to 2000L. Our dedicated team of experienced scientists is committed to excellence and has contributed to the development of over 200 biologics, supporting global clients in achieving successful IND applications with the FDA and NMPA.

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Scienta Lab

Scienta is a techbio company founded in 2021, dedicated to transforming drug development in immunology and inflammation. By combining proprietary disease-specific data assets with next-generation foundation model AI, Scienta bridges the translational gap that has long made I&I drug development among the most costly and failure-prone in the pharmaceutical industry. Despite decades of research and significant investment, the majority of immunology drug candidates still fail in clinical trials, largely due to poor translation from animal models to human patients. Phase II failure rates in I&I remain stubbornly high, driven by an inability to reliably predict which patients will respond to a given therapy before a costly trial begins. Scienta was built to address this challenge at its root. At the core of Scienta’s platform is EVA, the first cross-species, multimodal foundation model dedicated exclusively to immunology and inflammation. EVA learns from ImmunAtlas, Scienta’s proprietary curated database aggregating over 600,000 patient and biosample profiles across more than 30 immune-mediated diseases, integrating clinical, transcriptomic, histological, and proteomic data from 70+ tissues and more than 3 billion biological data points. EVA operates across the full drug development pipeline. At the discovery stage, it enables zero-shot target efficacy and gene function prediction to identify and prioritize the most promising therapeutic mechanisms. In preclinical development, it models cross-species and cross-disease molecular perturbations to anticipate how a drug candidate will impact immune networks in humans, going beyond what animal models alone can reveal. At the clinical stage, it supports patient stratification, treatment response prediction, and disease activity forecasting to identify the right patients for the right therapies before trials begin. In independent benchmarking across 39 immune-specific tasks spanning the drug development pipeline, EVA achieved state-of-the-art results, outperforming both generalist biological foundation models and conventional baselines. These results have been validated through peer-reviewed publications and presentations at leading biomedical and AI conferences. Scienta’s technology has been validated in concrete biopharma partnerships, with applications spanning dermatology, gastroenterology, rheumatology and neurology. Unlike generalist AI platforms or single-cell-focused tools, Scienta combines two capabilities rarely found together: high translational capability bridging preclinical to clinical development, and disease-specific explainability. Models are built to be interrogated, providing mechanistic interpretability that helps scientists understand why a prediction is made. This positions Scienta uniquely at the intersection of molecular precision and systemic, patient-level modeling. Scienta was co-founded by Camille Bouget (CEO, PharmD, previous experience across Sanofi, Sandoz, and Galapagos), Vincent Bouget (CSO, CentraleSupélec / MSc Biomedical Sciences), and Julien Duquesne (CTO, CentraleSupélec / MSc MVA, ENS Paris-Saclay). The company has raised 6.5 million euros in total funding, including support from the European Innovation Council’s EIC Accelerator, the EU’s flagship program for breakthrough deep-tech innovations.

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Schrödinger

Schrödinger is transforming molecular discovery through a physics-based computational platform that enables the rapid identification of highly optimized molecules for drug development and materials science. With over 30 years of R&D investment, our software is the industry standard—licensed by biotech, pharmaceutical, and industrial leaders, as well as academic institutions globally. Beyond software licensing, Schrödinger leverages its technology to advance a diverse portfolio of collaborative and proprietary drug discovery programs. By integrating predictive modeling with high-performance computing, we are accelerating the path to life-changing therapies and materials. | Schrödinger is transforming molecular discovery with its computational platform, which enables the discovery of novel, highly optimized molecules for materials design and drug development. Schrödinger’s software platform is built on more than 30 years of R&D investment and is licensed by biotechnology, pharmaceutical and industrial companies, and academic institutions around the world. Schrödinger also leverages the platform to advance a portfolio of collaborative and proprietary programs. Founded in 1990, Schrödinger has approximately 800 employees operating from 15 locations globally. To learn more, visit www.schrodinger.com, follow us on LinkedIn and Instagram, or visit our blog, Extrapolations.com. | Schrödinger is transforming the way materials are discovered. Schrödinger has pioneered a physics-based software platform that enables the discovery of novel materials more rapidly and at lower cost compared to traditional methods. The software platform is used by companies from organic electronics to consumer packaged goods, academic institutions, and government laboratories around the world. The platform has helped researchers in the food and beverage industry accelerate the design and development of sustainable food products.

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Rivia AG

x | RIVIA is the first Trial Intelligence platform with Agentic AI tools for modern sponsors. It brings all clinical and operational data into one single view, giving sponsors real-time control of the clinical development and saving up to 30% of the monitoring costs. All-in-one. All in real time. No more waiting on the CROs.

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Repligen

Repligen, a global life sciences company, develops and commercializes innovative bioprocessing technologies that increase efficiencies and flexibility in biotherapeutic manufacturing. As leaders in filtration, chromatography systems, process analytics and fluid management, we are committed to inspiring advances in bioprocessing. We are a trusted partner in the production of monoclonal antibodies, recombinant proteins, vaccines as well as cell and gene therapies. Named one of the fastest growing biotech companies in the USA, the majority of our 18 manufacturing sites are located in the United States (California, Massachusetts, New Jersey, New Hampshire, New York and Texas). Outside the United States, we have manufacturing sites in Estonia, France, Germany, Ireland, the Netherlands, and Sweden. | Repligen, a global, bioprocessing-focused life sciences company, provides innovative solutions for the advancement of biotherapeutic manufacturing. Experts in filtration, chromatography systems, process analytics, fluid management, and proteins, Repligen is a trusted partner serving the development and manufacture of a wide range of biologics, including cell and gene therapies, mRNA, monoclonal antibodies (mAbs), antibody–drug conjugates (ADCs), bispecific antibodies, and fusion proteins. Headquartered in Waltham, Massachusetts, USA, Repligen operates across 22 sites, including locations in the United States, Europe, and the Asia-Pacific region. | Inspiring advances in bioprocessing, Repligen is a trusted partner in process intensification, pre-packed chromatography and single-use filtration. Focused on cost and process efficiencies, our people and our technologies help meet critical bioproduction demands worldwide. As the recognized global leader in Protein A manufacturing, Repligen’s Protein A affinity ligands are routinely used to purify most of the world’s monoclonal antibodies.

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PreciGenome LLC

PreciGenome LLC, located in the heart of Silicon Valley in San Jose, California, is a leading innovator in developing state-of-the-art Lipid Nanoparticle (LNP) synthesis instruments and associated reagents, empowering researchers and pharmaceutical developers in their drug delivery endeavors. Our advanced microfluidic platforms enable precise and efficient LNP production, crucial for mRNA therapeutics and vaccine development. We offer comprehensive solutions that include both cutting-edge instrumentation, high-quality reagents and services, ensuring seamless integration and optimal results for our clients. At PreciGenome, we understand the critical nature of LNP formulation in modern drug delivery systems. Our technology delivers consistent particle size distribution and exceptional encapsulation efficiency, meeting the exacting standards required in pharmaceutical development. Whether you’re conducting early-stage research or scaling up for production, our systems provide the reliability and reproducibility essential for success in LNP-based therapeutics.

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Polish Investment & Trade Agency

The Polish Investment and Trade Agency is a mission driven, government entity, that is dedicated to promoting and growing the economy of Poland on a global stage. Anchored in Warsaw, with a network of nearly 60 foreign trade offices around the world, the Agency’s mission is to increase the awareness of Polish brands in international markets and to promote national products and services. This mission is accomplished by three pillars: promoting Polish exports, supporting the inflow of foreign direct investments to Poland and the implementation of Polish investments in the country, and the cultivation of partnerships with domestic and international stakeholders. | . | The Polish Investment and Trade Agency (PAIH) is Poland’s leading government agency dedicated to promoting Polish business on the international stage and attracting foreign investment to Poland. As a key partner for international companies looking to explore opportunities in Poland, PAIH provides comprehensive support to exporters and investors, bridging connections between global markets and the dynamic Polish economy. At the BIO International Convention, PAIH proudly coordinates the Polish National Pavilion, a platform showcasing Poland’s innovation potential in the life sciences sector. In collaboration with BioForum Central European Life Science Cluster, this year’s booth features 26 outstanding Polish companies representing the strength, diversity, and international ambitions of Poland’s biotech ecosystem. At this year’s BIO International Convention, Polish exhibitors will present cutting-edge solutions across four key categories: Drug Development, Diagnostics, Manufacturing, and Digital Solutions and Services. We invite all BIO International Convention participants to visit the Polish National Booth, meet our innovative companies, and explore partnership opportunities across the biotech value chain—from early-stage research and diagnostics to digital transformation and advanced manufacturing. | xxxx

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Pheiron GmbH

x | Pheiron is an AI research lab working towards a future of deterministic drug development. We can’t reliably predict which biology will work in humans. Pheiron builds causal models on primary human data to generate biological alpha: knowing what biology will work early enough to change the outcome of a drug program.

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