AAPharmaSyn, LLC (Ann Abor based and US owned) is a global research organization that provides Superior Drug Discovery Chemistry Solutions. We specialize in: 1. Medicinal Chemistry (hit to lead, lead optimization and scale up, SAR, etc. mg to 1 kg); 2. Process Research and Development (route scouting, route optimization, scale up, etc. up to 5 kg); 3. Custom and Exotic Research Tool (unique ADCs, lipids, flavonoids, carbohydrates, intermediates, etc.). AAPharmaSyn is built on the premise that application of the fundamental principles of synthetic organic chemistry toward salient problems leads to superior results. Our investment in how we solve problems and execute synthetic strategy saves money and time. | AAPharmaSyn, LLC is a US-based and owned global contract research organization (CRO) specializing in medicinal chemistry, drug discovery, process development, and non-GMP manufacturing. Headquartered in Ann Arbor, Michigan, the company was founded in 2006 by former Pfizer scientists and is staffed by senior chemists with deep expertise in organic synthesis, medicinal chemistry, and chemical process optimization. Since its inception, AAPharmaSyn has demonstrated consistent growth by delivering high-quality, reliable, and innovative solutions to a diverse client base—including government agencies, pharmaceutical and biotechnology companies of all sizes, and academic research institutions. The company’s core strengths include rigorous execution, scientific creativity, proactive problem-solving, and transparent communication. To further expand its capabilities and market reach, AAPharmaSyn actively pursues strategic collaborations with industrial partners and academic institutions, supporting the development of new products, acquisition of enabling platform technologies, and entry into emerging markets. Company Brief: 1. History: Founded in 2006 (ex-Pfizer). Based in Ann Arbor, MI (all work performed locally). BBB A+ rating. >800 projects successfully completed. 2. Team: Each team member has 10+ years of synthetic organic chemistry experience. All Ph.D.’s with multiple publications and patents. Academic pedigree: Yale, Princeton, Harvard, UC Berkeley, Purdue, UM. 3. Key Attributes: communication and problem-solving 4. Reputation: Our client testimonials speak to the value we deliver. (https://aapharmasyn.com/customer-testimonials/) Key services: • Medicinal Chemistry: high-throughput screening outcome triage, lead development, scaffold-hopping, structure-based design, structure activity relationship (SAR) development • Custom Organic and Peptide Synthesis: including ADC’s, complex carbohydrates, lipids, API impurities, intermediates, metabolites, etc. • Route Scouting and de novo Process Development: non-GMP scale-up (up to 5 kg batch size)
