Bioengineering AG is an indipendent and autonomous company that has been successfully turning customers’ ideas into reality since 1972. We offer comprehensive solutions in the areas of Engineering & Design, Services, Plants, Bioprocess Control, Lab & Pilot, and Components. We build plants for the production of vaccines, biosimilars, starter cultures and other products and develop automation solutions and components for controlling and monitoring the plants. Over 50 years of experience in plant construction and our innovative strength enable us to successfully realise even the most complex plants. | Bioengineering AG is an independent and autonomous company that has been successfully turning customers’ ideas into reality since 1972. We offer comprehensive solutions in the areas of Engineering & Design, Services, Plants, Bioprocess Control, Lab & Pilot, and Components. We build plants for the production of vaccines, biosimilars, starter cultures and other products and develop automation solutions and components for controlling and monitoring the plants. Over 50 years of experience in plant construction and our innovative strength enable us to successfully realise even the most complex plants. | Our fields of study may be diverse, but we are all engineers at heart. And citizens of the world. Here at Bioengineering, we work for those creating and making discoveries in laboratories and production facilities around the world. What unites us with them is a certain mindset: excellence. That’s what we fly the flag for, regardless of nationality. Our claim to excellence underlines our position as an intelligent and reliable partner who, with their bioreactors and fermentors, works in collaboration with the best companies in the world: inspiring excellence.
Biocatalysts Ltd
Biocatalysts are a global biotechnology company producing speciality enzymes at commercial scales for a variety of industries, such as food, flavour & fragrance, pharmaceutical, life sciences, fine chemicals and many more. Our state-of-the-art facility has a vertically integrated manufacturing process that optimises the large-scale production of novel enzymes, fermented proteins, and pharmaceutical biocatalysts. Biocatalysts offer off-the-shelf enzyme products and a customised enzyme development and manufacturing service. Biocatalysts have the tools and flexibility to provide tailored solutions specific to customers’ needs and can deliver rapid enzyme scale up from discovery through to full commercialisation. Biocatalysts develop and manufacture speciality enzymes for both food and non-food applications. More specifically this can include enzymes for flavour enhancement, the production of ‘enzyme modified cheese’, the hydrolysis of whey protein for the sports nutrition and infant formula markets, reprocessing of meat and fish to produce value-added ingredients, and for the hydrolysis of plant protein substrates to produce vegetable protein hydrolysates for increasing protein in a wide variety of food applications | Biocatalysts Ltd are a global biotechnology company producing speciality enzymes at commercial scales for a variety of industries, such as food, flavour & fragrance, pharmaceutical, life sciences, fine chemicals and many more. Our state-of-the-art facility has a vertically integrated manufacturing process that optimises the large-scale production of novel enzymes, fermented proteins, and pharmaceutical biocatalysts. Biocatalysts Ltd offer enzyme products and a customised enzyme development and manufacturing service. Biocatalysts Ltd have the tools and flexibility to provide tailored solutions specific to customers’ needs and can deliver rapid enzyme scale up from discovery through to full commercialisation. Biocatalysts Ltd develop and manufacture speciality enzymes for both food and non-food applications. More specifically this can include enzymes for flavour enhancement, improving functionality and digestibility of plant and animal-derived proteins, as well as enzymes used in fundamental molecular biology techniques to advance drug discovery, and modify and manipulate DNA for diagnostic and therapeutic purposes. | BRAIN Biocatalysts is a UK-based enzyme development and manufacturing company with over 40 years of experience supplying customised enzyme solutions to global markets. As part of BRAIN Biotech Group, BRAIN Biocatalysts combines deep expertise in fermentation, scale-up and downstream processing with cutting-edge enzyme discovery and engineering capabilities. BRAIN Biocatalysts Life Science Solutions was recently launched as a dedicated brand focused on delivering fully integrated, end-to-end enzyme development for the pharmaceutical and life science industries. From early discovery through to large-scale manufacturing, the brand offers tailored and scalable enzyme solutions – underpinned by a transparent IP model and supported by world-class bioprocessing infrastructure.
BINEX Co., Ltd.
Binex has been a true biologics CDMO partner with a reliable GMP production record over 1,111 batches providing top quality CDMO service to its clients. Binex offers full range of CDMO services from cell-line development to GMP manufacturing for drug substance and drug product and has production lines ranging from 180L to 5,000L for mammalian cell culture and microbial fermentation. Binex has been globally supplying clinical materials and commercial products (mAbs, bispecific mAbs, Fc-fusion proteins, recombinant proteins, DNA vaccines, etc.) to our CDMO clients who have established time-honored business relationship with Binex. | BINEX is your reliable Contract Development and Manufacturing Organization (CDMO) partner that complies with GMP and EU GMP requirements. Based on our global track records and vast GMP manufacturing experience of drug substance and drug product, we are committed to provide client-oriented CDMO services. We cater to clients utilizing our facilities, which offer a diverse range of bioreactors, as well as our accumulated know-how in manufacturing service across mammalian cell cultivation and microbial fermentation.
BiBo Pharma
BiBo Pharma is a full spectrum CDMO covering the entire CMC lifecycle of biologics. BiBo Pharma has multiple technology platforms, including microbial fermentation, mammalian cell culture, gene and cell therapy, XDC & GMP facility engineering service. Empowered by PanFlex®-Engineering, BiBo’s specialist team innovated the world’s first and largest 30,000 L stainless steel ultra-large bioreactor for mammalian cell culture production, and 30,000L high cooling capacity fermenters enabling ultra-high-cell-density fermentation. BiBo Pharma, which started in 2014 based in Boston, USA, now has two R&D centers and three GMP facilities in operation globally. BiBo established the first GMP facility P01 site in Shanghai in 2019, the P02 GMP site in 2021, and the P03 GMP site in 2023. Two more mega-GMP facilities, P04 and P05, have been initiated and will be in operation in the next three to seven years. BiBo’s core team members come from world-leading companies in the US, Europe, and China. BiBo has accomplished over 100 biologics projects, including over 30 in clinical and commercial stages. Our CMC service package includes cell line and strain development, process development, analytical development, formulation development, toxicological and GMP production of drug substance and drug product, process characterization, and large-scale production. BiBo is the world leader in the fourth wave of biomanufacturing. Not only has BiBo established the world’s first and largest 30,000L ultra-large mammalian production line, but it has also achieved a 100% success rate on all scale-up projects by applying our innovative “success on the first time” system.
Avid Bioservices, Inc.
Avid Bioservices (NASDAQ: CDMO) is a dedicated contract development and manufacturing organization (CDMO) focused on development and CGMP manufacturing of biologics. The company provides a comprehensive range of process development, CGMP clinical and commercial manufacturing services for the biotechnology, biopharmaceutical, and cell & gene therapy industries. With over 30 years of experience producing biologics, Avid’s services include CGMP clinical and commercial drug substance manufacturing, bulk packaging, release and stability testing and regulatory submissions support. For early-stage programs the company provides a variety of process development activities, including cell line development, upstream and downstream development and optimization, analytical methods development, testing and characterization. The scope of our services ranges from standalone process development projects to full development and manufacturing programs through commercialization. www.avidbio.comwww.avidbio.com | Avid Bioservices, a dedicated biologics CDMO, is transforming the CDMO experience. From concept to market, we are your advocate. We have more than 30 years of unrivaled expertise manufacturing biologics and a leadership team with a 10-year average operational leadership tenure. Our world-class mammalian protein facilities are located in Orange County, CA. We’ve produced more than 250 commercial batches, and 5 commercial products marketed in 90+ countries. We maintain the highest level of compliance with a dedication to continuously improving our quality systems and manufacturing processes. For more than 10 years, we’ve maintained a flawless quality track record which we’re committed to uphold. From early-stage to late-stage, concept to market, every part of our process is personalized. We’re your advocates, your trusted experts, your true partners. For more information, visit AvidBio.com. | Avid Bioservices, a dedicated biologics CDMO, is transforming the CDMO experience. From concept to market, we are your advocate. We have more than 30 years of unrivaled expertise manufacturing biologics and a leadership team with a 10-year average operational leadership tenure. Our world-class mammalian protein facilities are located in Orange County, CA. We’ve produced more than 250 commercial batches, and 5 commercial products marketed in 90+ countries. We maintain the highest level of compliance with a dedication to continuously improving our quality systems and manufacturing processes. For more than 10 years, we’ve maintained a flawless quality track record which we’re committed to uphold. From early-stage to late-stage, concept to market, every part of our process is personalized. We’re your advocates, your trusted experts, your true partners.
AsymBio
Asymchem (Stock Code: 002821.SZ/6821.HK) is a global leading CDMO founded in 1995, offering integrated solutions across the pharmaceutical lifecycle—from R&D to commercial production. Specializing in small molecules, chemical macromolecules, biologics, and synthetic biology, Asymchem operates R&D and manufacturing facilities in China, the U.S., and the U.K., supported by a team of over 9,000 professionals . Its subsidiary, AsymBio, is committed to being a technology-driven CDMO with a global vision and best-in-class solutions for bioconjugates, antibodies, etc. With a proven track record, AsymBio is the innovative, reliable and client centric CDMO partner driven for your success in the competitive pharmaceutical landscape
Ascendia Pharmaceutical Solutions
Ascendia Pharmaceutical Solutions specializes in complex formulation development and manufacturing of pharmaceutical and biologic products using a suite of novel formulation technologies. We provide formulation, analytical, and manufacturing services to pharmaceutical companies, working collaboratively to provide innovative solutions to challenging drug delivery problems and to create advanced medicines. CREATING FORMULATIONS FOR CHALLENGING MOLECULES Ascendia’s expertise involves finding the most effective method of drug delivery for poorly soluble and/or bioavailable molecules. Our comprehensive range of capabilities enables clients to optimize their drug product formulation prior to initiating expensive clinical development. Ascendia provides practical, customized formulation solutions that enable rapid advancement of compounds from discovery to clinical testing. We create trial formulations suitable for PK and tox studies using our nano-emulsion, amorphous solid dispersion, controlled release, LNP and other nanoparticle engineering approaches. We conduct preformulation testing, formulation approach comparisons, dosage form design, and formulation optimization. By working with Ascendia, our clients can quickly determine the feasibility of multiple technical approaches in parallel, thus improving the probability of formulation success and reducing the time required to make critical early-stage formulation decisions. cGMP MANUFACTURING Following formulation selection and optimization, Ascendia can quickly transition a development program to cGMP manufacturing of first-in-man clinical materials. With both aseptic and non-aseptic manufacturing suites in its New Jersey (USA) facility, the company can handle various dosage forms, including those for oral, topical or parenteral administration. Ascendia offers its manufacturing services to third parties that need a CDMO partner for their formulations advancing from preclinical to clinical stages of development. LIFE-CYCLE MANAGEMENT AND 505(b)(2) PRODUCT DEVELOPMENT Ascendia is dedicated to the solubility, bioavailability and stability enhancement of difficult-to-formulate compounds. Our proprietary product development programs focus on creating novel specialty pharmaceutical products that are improved versions of existing medicines. We develop oral, topical and injectable products for clients via the 505(b)(2) NDA pathway, as well providing formulation development and manufacturing for complex generic (ANDA) products.
Ascend Advanced Therapies-ABL
X Ascend Advanced Therapies and ABL Inc. form a premier CDMO alliance with 50+ years of viral manufacturing expertise. We deliver high-quality, cost-effective development and commercial-scale production of gene therapies, oncolytics, and vaccines—accelerating time-to-market for biotech innovators across multiple advanced therapy modalities.