About

About Juzen Chemical Corporation Outsourcing of intermediates, APIs, and drug products has become an essential and strategic practice for many pharmaceutical manufacturers. As a trusted contract manufacturer of APIs and key intermediates, Juzen Chemical leverages its extensive experience and technical expertise to meet the diverse needs of our customers at every stage — from new drug development to the production of existing medicines. Business Fields: Oligonucleotide CDMO Services: Juzen Chemical offers comprehensive solutions for the development and manufacturing of nucleic acid pharmaceuticals. We provide flexible and reliable support tailored to customer needs, covering everything from laboratory-scale sample synthesis to manufacturing process development and GMP-compliant production. To further enhance production efficiency, Juzen Chemical has adopted the Contichrom® continuous purification chromatography system, enabling the high-quality production of nucleic acid oligomers. In addition, we have the capability to develop and manufacture novel modified nucleic acid monomers, allowing for seamless, end-to-end production from monomer synthesis to oligomer manufacturing. This integrated approach ensures smooth transitions across all stages of drug development and commercial production, delivering optimal solutions and high productivity to our customers. Small Molecule CDMO Services: At our Toyama site, Juzen Chemical provides contract manufacturing services for active pharmaceutical ingredients (APIs) and intermediates. Our facilities are equipped with a wide range of manufacturing systems capable of handling production volumes from gram scale to ton scale, supporting every stage from clinical trials to commercial supply. This comprehensive capability ensures a seamless and efficient contract manufacturing process. Leveraging our extensive manufacturing expertise, we have established a highly flexible system capable of managing complex processes. We specialize in ultra-low temperature reactions, high-temperature reactions, and hydrogenation reactions, achieving stable production even at ton-scale volumes. In addition, we have developed a robust quality control system aligned with global standards, operating under GMP guidelines in compliance with the United States Pharmacopeia (USP), Japanese Pharmacopoeia (JP), and European Pharmacopoeia (EP). This enables us to consistently deliver highly reliable products that meet and exceed our customers’ expectations. CMC Solution Services: To accelerate drug development, Juzen Chemical offers a comprehensive One-Stop CMC Solution Service across two locations: our Toyama site and the Shonan site, located within the Shonan Health Innovation Park. Through this integrated approach, we provide end-to-end support across all development stages, including manufacturing process studies, analytical method development, and optimization of scale-up processes for mid- to late-stage projects. Our services ensure compliance with regulatory standards such as the ICH Q3 series and facilitate the acquisition of data required for regulatory submissions. Backed by a team of experienced chemists, we deliver tailored, professional support to meet the specific needs of each project, responding swiftly and effectively to drive project success.