About

About Beth Bioinformatics Co., Ltd Beth Bioinformatics (BethBio) is a solution provider for novel vaccine development. We invent and deliver innovative solutions to empower vaccine manufacturers design effective antigens, improve vaccine performance and streamline clinical trials. BethBio holds the world’s most accurate method Beth-1 for predicting future evolution of influenza virus. By modelling viral mutations, we design vaccine antigens that generate higher vaccine efficacy (VE) against future circulating strains and a longer protection period. We also cover other pathogens such as SARS-CoV-2, RSV and Monkeypox. BethBio has also developed a first-of-its-kind computation platform for accurate VE estimation without first requiring vaccination. It provides strategic benefits throughout the vaccine development cycle, from supporting antigen optimization to refining clinical trial designs and product planning. The technology has been used to support clients in drug applications and was accepted as supporting evidence by regulatory authority. Our PCO codon optimization preserves correct protein conformation while optimizing expression and other properties, outperforms the best alternative methods in various platforms and is adopted by vaccine developers in multiple countries. We also offer a unique epitope screening system through genome stability evaluation, which facilitates the identification of broadly reactive epitopes and development of therapeutic vaccines. We look forward to collaborating with you.